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There are currently 11 members of the PRMT family that share conserved catalytic domains (black). PRMT9 has four isoforms. PRMT7 and PRMT10 harbour two catalytic domains. The histone substrate of each enzyme, the type of modification that it catalyses, and the biological functions of modification are shown. DNMT3, DNA methyltransferase 3; ER, oestrogen receptor.
