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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Exp Neurol. 2017 Mar 22;292:145–153. doi: 10.1016/j.expneurol.2017.03.014

Fig. 3. EAAT2-D504N protects SOD1-G93A mice.

Fig. 3

(A) The lifespan of SOD1-G93A mice was significantly extended in mice with the EAAT2-D504N mutation. (B) Onset of disease, as determined by age at peak weight, however, was unaltered in EAAT2 mutant mice. (C) The duration of disease, measured from age of onset to age of end stage was significantly delayed in EAAT2-D504N mice.