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. Author manuscript; available in PMC: 2017 May 16.
Published in final edited form as: Crit Rev Immunol. 2015;35(1):49–57. doi: 10.1615/critrevimmunol.2015012558

FIG. 2.

FIG. 2

Phenotypes of presently described Breg subsets. Prior activation by TLR and/or BCR signals appears to be required for generation of IL10-producing, IL35-producing, and IL10-/IL35-producing Bregs expressing overlapping cell-surface markers shared by Bregs and conventional B cells.