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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Physiol Behav. 2017 Feb 14;176:40–49. doi: 10.1016/j.physbeh.2017.02.011

Figure 5.

Figure 5

Ghsr knockdown in the LHA abolishes food reward impact of LHA-targeted ghrelin. Ghrelin increased the amount of sucrose rewards earned (A) and the number of active lever presses for sucrose (B) in control rats but not in rats with Ghsr knocked down. Similarly Ghsr knockdown was sufficient to abolish the food-seeking behavior potentiation induced by ghrelin (C). No changes in locomotor activity were detected (D). The knockdown was, however, not sufficient to attenuate the ghrelin-induced elevation in chow intake (E). Data are expressed as mean ±SEM. n=12 (female rats). * p < 0.05, ** p < 0.001, #p < 0.1.