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. Author manuscript; available in PMC: 2017 Jun 19.
Published in final edited form as: Mucosal Immunol. 2016 Nov 16;10(4):971–982. doi: 10.1038/mi.2016.98

Figure 4. NOD2 regulates Th2-mediated chronic intestinal inflammation.

Figure 4

(A) Representative 3D-SM image of involved and uninvolved areas of SAMP WT and SAMP × NOD2−/− mice from which samples were derived. (B) GATA-3, (C) IL-4, IL-5, and IL-13 expression during chronic ileitis (30 wks). *** P < 0.0001 (n=6-12), Student’s t test; data are represented as mean ± SEM. Protein lysates from (D) ilea and (E) MLNs from 30-wk-old SAMP WT and SAMP × NOD2−/− mice immunoblotted with antibodies against phosphorylated-STAT6, total-STAT6, GATA-3, IL-13, and actin (n>3).

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