Figure 7. 16S rRNA microbial community analysis shows that bacterial community changes before and after DSS-induced colitis do not predict the presence of Nod2 deletion in SAMP mice.
Following the fecal homogenization protocol, fecal samples from SAMP WT and SAMP × NOD2−/− mice were collected before and after 7 days of 3% DSS treatment (n=3-6/group, 2-3 experiments). (A) Principal coordinate analysis of 16S rRNA microbial community data before and after DSS. (B) Box plot of the normalized 16S amplicon Log2 abundance for the six most abundant bacterial phyla for all experimental mice.