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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Free Radic Biol Med. 2016 Nov 16;107:170–178. doi: 10.1016/j.freeradbiomed.2016.11.024

Fig. 4.

Fig. 4

Diffusive behavior of WT and wedge variant DNA glycosylases. A, B, and C show the mean diffusion constant for Fpg (A), Nei (B), and Nth (C) wild-type and wedge variants scanning along undamaged lambda DNA and lambda DNA containing specific damages. The damaged purines for Fpg (A) were generated using methylene blue plus visible light, while damaged pyrimidines for Nei (B) and Nth (C) were generated using osmium tetroxide. The details for these experiments can be found in Ref. [70] (***P < 0.001).