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. 2017 May 16;7:1984. doi: 10.1038/s41598-017-01802-4

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Differences in IBD-sharing between Southern Italian and Southern Balkan population groups. Vectors of IBD-sharing with the 35 comparison populations reported on the x-axis were pairwise subtracted between pairs of Southern Balkan and/or Southern Italian population groups. The plots at the bottom of the figure provide a schematic representation of the pairwise-subtracting procedure (left: IBD-sharing of a Southern Balkan group with all comparison populations; centre: IBD-sharing of a Southern Italian group with all comparison populations; right: difference in IBD-sharing between the two considered groups). Comparison populations for which we observed differences in IBD-sharing between the two tested groups exceeding the lower (0.10 percentile) or the upper (0.90 percentile) bounds of the distribution are marked by coloured boxes in the table (green: Grp1 > Grp2, red Grp2 > Grp1). Significant differences in IBD-sharing, after the grubbs.test for significance (R software package outliers [v. 0.14] Komsta, L. Outliers: Tests for outliers. R package version 0.14. URL: https://CRAN.R-project.org/package=outliers (2011)), are indicated by corresponding p-values (* P-value < 0.05, **P-value < 0.01, ***P-value < 0.001). Southern Italian and Southern Balkan compared population groups were considered as follow: SSI-Extreme (Apulia-LE, Basilicata-MT and the westernmost province of Sicily-TP); SSI-Central (including the remaining populations of Central-Eastern Sicily and Calabria); Mediterranean Greek-speaking islands (Crete, Cyprus and Anatolian/Dodecanese Greece); Continental Southern Balkan populations (Albania, North-Central Greece and Peloponnesus). The geographical map has been plotted using the R software [v.3.2.4] (R: A Language and Environment for Statistical Computing, R Core Team, R Foundation for Statistical Computing, Vienna, Austria (2016) https://www.R-project.org).