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. 2017 May 16;7:1953. doi: 10.1038/s41598-017-02030-6

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Neurological symptoms and imaging findings. (A) Prevalence of neurological symptoms (focal neurological signs [FNS] and signs of global brain dysfunction) in all patients with symptomatic hypotonic hyponatremia in our cohort (n = 140). (B) Results of neuroimaging studies (cCT and/or cMRI) in 95 of 140 patients (67.8%). Incidental findings (n = 38): imaging findings, which were not related to acute symptoms (multiple findings were permitted): general cerebral atrophy (n = 20), age-related periventricular white matter changes (n = 16), old ischemic stroke (n = 15), arteriosclerosis (n = 15), calcification of pineal gland/choroid plexus (n = 8), signs of former neurosurgical interventions (n = 3), signs of old fracture (n = 2).