Table 2.
Clinical progress of children with mitochondrial disease (n = 53).
| Characteristic | Value | |
|---|---|---|
| Number of organs involved | 1.54 ± 0.93 | |
| Organ involvement | CNS only | 34 (64) |
| CNS + other organs | 19 (36) | |
| Severity of epilepsy | No epilepsy | 10 (19) |
| Drug-responsive epilepsy | 18 (33) | |
| Drug-resistant epilepsy | 26 (48) | |
| Diffuse brain atrophy on MRI | Normal | 22 (42) |
| Mild | 26 (49) | |
| Severe | 5 (9) | |
| Clinical progress | Improving | 1 (2) |
| Static | 20 (38) | |
| Mildly deteriorating | 22 (42) | |
| Severely deteriorating | 10 (19) | |
Data given as total number (percentage) or mean ± SD.
CNS, central nervous system; MRI, magnetic resonance imaging.