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Gain-of-function interactions in the A172F FGFR2b-FGF10 dimer. Detailed view of the receptor-receptor interface. The side chains of interacting residues leading to increased receptor-receptor contacts are displayed. On the right is a view of the whole structure in the exact orientation that the detailed view shows, with the region of interest boxed. D2, D3, and FGF10 are colored as in Fig. 1.
