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. 2017 May 17;8:313. doi: 10.3389/fphys.2017.00313

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Copyright © 2017 Marzbanrad, Khandoker, Kimura, Palaniswami and Clifford.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The estimated GA using cardiac valve timings vs. the GA based on CRL as a gold standard are shown for 30 abnormal cases. The 95% Confidence Interval (CI) for healthy cases (as shown in Figure 4) and y = x line are also shown for comparison. The abnormality types are specified for the cases with estimated GA being outside the 95% CI. More details can be found in Table 4. (WPW, Wolff-Parkinson-White syndrome; VSD, Ventricular Septal Defect; PA, Pulmonary Atresia; ASD, Atrial Septal Defect; CDH, Congenital Diaphragmatic Hernia; CA, Chromosomal Aberration; AV block, Atrioventricular block; SA, Single Atrium; CAV, Cardiac Allograft Vasculopathy; CAVC, Common Atrioventricular Canal; PS, Polysplenia Syndrome; CHD, Congenital Heart Disease; NIHF, Nonimmune Hydrops Fetalis).