Table 5.
Prevalence of arterial hypertension and diabetes according to MWA levels in CMI and IIH patients
Total | Comorbidity | Crude estimate | Age‐adjusted estimate | ||
---|---|---|---|---|---|
Yes (%) | No (%) | OR (95% CI), p‐value | OR (95% CI), p‐value | ||
Arterial hypertension | |||||
CMI: MWA <4 mmHg | 12 | 1 (8.3) | 11 (91.7) | 0.49 (0.06–3.83), p = .500 | 1.77 (0.20–16.1), p = .610 |
CMI: MWA ≥4 mmHg | 36 | 2 (5.6) | 34 (94.4) | 0.32 (0.08–1.33), p = .117 | 1.01 (0.23–4.54), p = .987 |
HUNT3 | 42,461 | 6,597 (15.5) | 35,864 (84.5) | Control group | Control group |
IIH: MWA <4 mmHg | 8 | 0 (0) | 8 (100) | Not defined | Not defined |
IIH: MWA ≥4 mmHg | 44 | 7 (15.9) | 37 (84.1) | 1.02 (0.46–2.31), p = .946 | 4.11 (1.64–10.3), p = .003 |
HUNT3 | 42,461 | 6,597 (15.5) | 35,864 (84.5) | Control group | Control group |
Diabetes | |||||
CMI: MWA <4 mmHg | 12 | 0 (0) | 12 (100) | Not defined | Not defined |
CMI: MWA ≥4 mmHg | 36 | 2 (5.6) | 34 (94.4) | 1.66 (0.40–6.92), p = .486 | 4.02 (0.94–17.3), p = .061 |
HUNT3 | 42,461 | 1,453 (3.4) | 41,008 (96.6) | Control group | Control group |
IIH: MWA <4 mmHg | 8 | 3 (37.5) | 5 (62.5) | 16.9 (4.0–70.9), p < .001 | 50.2 (10.8–232.5), p < .001 |
IIH: MWA ≥4 mmHg | 44 | 2 (4.6) | 42 (95.4) | 1.34 (0.33–5.56), p = .683 | 3.24 (0.76–13.8), p = .111 |
HUNT3 | 42,461 | 1,453 (3.4) | 41,008 (96.6) | Control group | Control group |
CMI, Chiari malformation type I; MWA, mean wave amplitude; HUNT3, The HUNT3 Survey; IIH, idiopathic intracranial hypertension; OR, odds ratio; CI, confidence interval.
Data presented as numbers (percentages in parenthesis) and statistically assessed with logistic regression analysis.