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. 2017 May 2;2017:2530270. doi: 10.1155/2017/2530270

Table 1.

miRNAs studied and some of their targets that are involved in AD-related pathways.

ID miRNA Sequence Target
MIMAT0000104 hsa-miR-107 50-agcagcauuguacagggcuauca-72 PLAG1, BACE1, CDK6, GRN, DAPK 1, PTEN,
NOTCH 2, NFIA, SERBP1
MIMAT0000765 hsa-miR-335-5p 16-ucaagagcaauaacgaaaaaugu-38 TNC, RASA1, IGFR1, SP1, APBB2
MIMAT0000083 hsa-miR-26b-5p 12-uucaaguaauucaggauaggu-32 SLC17A6, (DNP1/vGLUT2)

Note. PLAG1: pleiomorphic adenoma gene 1; BACE1: beta-site APP-cleaving enzyme 1; CDK6: cyclin-dependent kinase 6; GRN: granulin; DAPK 1: death-associated protein kinase 1; PTEN: phosphatase and tensin homolog; NOTCH 2: Notch 2; NFIA: nuclear factor I/A; SERBP1: SERPINE1 mRNA-binding protein 1; TNC: tenascin C; RASA1: RAS p21 protein activator (GTPase-activating protein) 1; IGFR1: insulin-like growth factor 1 receptor; SP1: Sp1 transcription factor; APBB2: Aβ precursor protein binding family B member 2; SLC17A6 (DNP1/vGLUT2): solute carrier family 17 member 6 (vesicular glutamate transporter).