Table 3. Activity of liver antioxidant glutathione in mice fed normocholesterolaemic diet and hypercholesterolaemic diet.
Activity µM/mg of protein |
Normocholesterolaemic diet | Hypercholesterolaemic diet | |||
---|---|---|---|---|---|
Control | Wine lees | Cholesterol | Wine lees+cholesterol | ||
GSH | (20.5±0.3)a | (24.2±0.3)b | (16.9±0.4)c | (22.1±0.3)a | |
GSSG | (0.3±0.06)a | (0.2±0.08)b | (0.3±0.08)a | (0.3±0.06)b | |
GSH/GSSG | (62.1±12.1)a | (89.6±10.2)b | (49.7±15.3)c | (76.2±13.5)d |
Values are expressed as mean±S.D. GSH=reduced glutathione, GSSG=glutathione disulfide. Mean values with different letters in superscript are significantly different (p<0.05)