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Thiopurine-associated lymphopenia is due to decreased B cells. CD3-, CD19+ B cell (A) counts per ml of blood were compared between cohorts, as were CD19+, CD27-, IgD+, CD38- naïve B cells (B), CD19+, CD27+, IgD-, CD20+, CD38- memory B cells (C), and CD19+, CD27-, IgD+, CD38+ transitional B cells (D). P values reflect two-tailed Mann-Whitney non-parametric comparisons.
