Table 7.
Case-control studies for association of chronic HCV infection with oral cancer (OC).
| Author | Country | Study design | Sample size (n) |
HCV (+) cases/total cases (%) |
HCV (+) controls/total controls (%) | Factors adjusted | OR (95% CI) | P value |
|---|---|---|---|---|---|---|---|---|
| Nagao et al. [43] | Japan | (a) Anti-HCV ab | 204 | (a) 24/100 (24) | (a) 11/104 (10.6) | None | NA | (a) <0.05 |
| (b) HCV RNA | (b) 17/100 (17) | (b) 4/104 (3.9) | (b) <0.05 | |||||
| Takata et al. [44] | Japan | Anti-HCV ab∗ Hospital-based OC IT∗∗ |
4402 | 13/343 | 25/270 | Age | 0.4 (0.2–0.9) | <0.05 |
OR: odds ratio; CI: confidence interval; NA: not available; ∗∗IT—impacted teeth (controls); ∗anti-HCV antibodies were compared among patients with OC and IT.