Table 1.
Collection dates, van-genotypes, MLST sequence types (all isolates) and antimicrobial resistance expression (only patient isolates) of VRE strains
| Isolate no. | Collection date | van-genotype | MLST- ST | AMP | SAM | AX | AMC | PRL | TPZ | IPM | CIP | LEV | TEC | QD | TGC | LNZ | F | SXT | CN-HLR | S-HLR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P1 | 2015–03-01 | vanA | 203 | r | r | r | r | r | r | r | r | r | r | s | s | s | r | r | + | + |
| P2 | 2015–03-18 | vanB | 192 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | − |
| P3 | 2015–04-16 | vanB | 192 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | − |
| P4 | 2015–04-26 | vanA | 117 | r | r | r | r | r | r | r | r | r | r | s | s | s | s | r | + | − |
| P5 | 2015–05-01 | vanB | 80 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | − | − |
| P6 | 2015–05-22 | vanA | 769 | r | r | r | r | r | r | r | r | r | r | s | s | s | s | r | − | + |
| P7 | 2015–05-22 | vanB | 192 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | − |
| P8 | 2015–05-23 | vanA | 769 | r | r | r | r | r | r | r | r | r | r | s | s | s | s | r | − | + |
| P9 | 2015–05-23 | vanB | 117 | r | r | r | r | r | r | r | r | r | s | s | s | s | r | r | + | + |
| P10 | 2015–05-23 | vanA + vanB | 17 | r | r | r | r | r | r | r | r | r | s | s | s | s | r | r | + | + |
| P11 | 2015–05-23 | vanB | N/A | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | − | + |
| P12 | 2015–05-23 | vanB | 192 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | − | − |
| P13 | 2015–05-24 | vanB | N/A | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | − | + |
| P14 | 2015–05-25 | vanA | 769 | r | r | r | r | r | r | r | r | r | r | s | s | s | s | r | + | + |
| P15 | 2015–05-28 | vanA | 203 | r | r | r | r | r | r | r | r | r | r | s | s | r | r | r | + | − |
| P16 | 2015–06-02 | vanB | 192 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | − |
| P17 | 2015–06-02 | vanA | 769 | r | r | r | r | r | r | r | r | r | r | s | s | s | s | r | + | + |
| P18 | 2015–06-02 | vanB | 192 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | − |
| P19 | 2015–06-07 | vanA | 769 | r | r | r | r | r | r | r | r | r | r | s | s | s | s | r | + | + |
| P20 | 2015–06-08 | vanB | 192 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | − |
| P21 | 2015–06-09 | vanA | 203 | r | r | r | r | r | r | r | r | r | r | s | r | s | r | r | − | + |
| P22 | 2015–06-09 | vanA | 203 | r | r | r | r | r | r | r | r | r | r | s | r | s | r | r | − | + |
| P23 | 2015–06-09 | vanB | 192 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | − | − |
| P24 | 2015–06-09 | vanB | 192 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | − |
| P25 | 2015–06-16 | vanB | 192 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | − |
| P26 | 2015–06-16 | vanB | N/A | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | − | + |
| P27 | 2015–06-17 | vanA | 203 | r | r | r | r | r | r | r | r | r | r | s | s | s | r | r | − | + |
| P28 | 2015–06-19 | vanB | 192 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | − |
| P29 | 2015–06-23 | vanB | 192 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | − |
| P30 | 2015–06-23 | vanB | N/A | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | − | + |
| P31 | 2015–07-01 | vanA | 192 | r | r | r | r | r | r | r | r | r | r | s | s | s | r | r | + | + |
| P32 | 2015–07-02 | vanB | 17 | r | r | r | r | r | r | r | r | r | s | s | s | s | r | r | − | + |
| P33 | 2015–07-02 | vanB | 80 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | − |
| P34 | 2015–07-07 | vanB | 192 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | − |
| P35 | 2015–07-07 | vanA | 203 | r | r | r | r | r | r | r | r | r | r | s | s | s | r | r | + | + |
| P36 | 2015–07-12 | vanB | N/A | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | − | + |
| P37 | 2015–07-16 | vanB | 192 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | − |
| P38 | 2015–07-21 | vanB | N/A | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | − | + |
| P39 | 2015–07-21 | vanB | N/A | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | − | + |
| P40 | 2015–07-21 | vanB | N/A | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | − | + |
| P41 | 2015–07-21 | vanB | 192 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | + |
| P42 | 2015–07-21 | vanA | 203 | r | r | r | r | r | r | r | r | r | r | s | s | s | r | r | + | + |
| P43 | 2015–07-30 | vanB | N/A | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | − |
| P44 | 2015–07-30 | vanB | N/A | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | + |
| P45 | 2015–07-30 | vanA | 203 | r | r | r | r | r | r | r | r | r | r | s | s | s | r | r | − | + |
| P46 | 2015–08-06 | vanB | N/A | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | − |
| P47 | 2015–08-06 | vanB | 192 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | − |
| P48 | 2015–08-13 | vanB | N/A | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | + |
| P49 | 2015–08-20 | vanB | N/A | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | − | + |
| P50 | 2015–08-31 | vanB | N/A | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | − | + |
| P51 | 2015–09-02 | vanB | 80 | r | r | r | r | r | r | r | r | r | s | i | s | s | s | r | + | + |
| P52 | 2015–09-07 | vanB | N/A | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | + |
| P53 | 2015–10-08 | vanB | 80 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | + |
| P54 | 2015–10-19 | vanB | 80 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | + |
| P55 | 2015–10-19 | vanB | N/A | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | − | + |
| P56 | 2015–10-26 | vanB | 80 | r | r | r | r | r | r | r | r | r | s | s | s | s | s | r | + | − |
| P57 | 2015–11-25 | vanB | N/A | r | r | r | r | r | r | r | r | r | r | s | s | s | s | r | − | + |
| P58 | 2015–11-30 | vanA | 203 | r | r | r | r | r | r | r | r | r | r | s | s | s | r | r | − | − |
| P59 | 2015–12-21 | vanA | 203 | r | r | r | r | r | r | r | r | r | r | s | s | s | r | r | + | + |
| P60 | 2015–12-21 | vanA | 203 | r | r | r | r | r | r | r | r | r | r | s | s | s | r | r | + | + |
| Pref | 2015–05-15 | vanA | 192 | r | r | r | r | r | r | r | r | r | r | s | s | s | r | r | + | + |
| E1 | 2015–05-11 | vanB | 192 | |||||||||||||||||
| E2 | 2015–05-11 | vanB | 192 | |||||||||||||||||
| E3 | 2015–05-11 | vanB | 192 | |||||||||||||||||
| E4 | 2015–05-11 | vanB | 192 | |||||||||||||||||
| E5 | 2015–05-11 | vanB | 769 | |||||||||||||||||
| E6 | 2015–05-11 | vanA | 192 | |||||||||||||||||
| E7 | 2015–05-19 | vanB | 192 | |||||||||||||||||
| E8 | 2015–06-02 | vanB | 80 | |||||||||||||||||
| E9 | 2015–06-02 | vanB | 192 | |||||||||||||||||
| E10 | 2015–06-02 | vanB | 80 | |||||||||||||||||
| E11 | 2015–06-02 | vanB | N/A |
AMP ampicillin, SAM ampicillin/sulbactam, AX amoxicillin, AMC amoxicillin/clavulanic acid, PRL piperacillin, TPZ piperacillin/tazobactam, IPM imipenem, CIP ciprofloxacin, LEV levofloxacin, CN-HLR gentamicin-high level resistance, S-HLR streptomycin-high level resistance, TEC teicoplanin, QD quinopristin/dalfopristin, TGC tigecyclin, LNZ linezolid, F nitrofurantoin, SXT timetoprim/sulfamethoxazole, MLST Multi Locus Sequence Typing, VRE Vancomycin resistant enterococci
r resistant, s susceptible