Fig. 2.

a. Simplified scheme of central carbon metabolism of the GEM: 1) Glycolysis. 2) lactate fermentation. 3) Propionate fermentation. 4) Acrylate pathway. 5) Pyruvate dehydrogenase. 6) Pyruvate formate-lyase. 7) Butyrate fermentation. 8) Acetate fermentation. 9) Acetogenesis via Wood-Ljungdahl pathway. 10) Ethanol fermentation. 11) butyryl-CoA:acetate-CoA transferase. Pathways are reversible - arrow directions indicate the most common direction; b. Metabolite dynamics over time. At time 0 only glucose is available