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. 2005 Jan 11;2(1):e18. doi: 10.1371/journal.pmed.0020018

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Copyright: © 2005 Pedrini et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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SweAPP N2a cells were treated for 24 h with simvastatin (Sim, 1 μM), FTI-1 (5 μM), mevalonic acid (0–100 μM), or combinations as indicated. Levels of sAPP_α were evaluated by western blot as described in Methods. This figure is representative of the results of two independent experiments. C, control.