Table 1.
Effects of different vaccine candidates on BCG-induced rabbit skin lesions.
| Time of onset of liquefaction (days post-infection) | Time of ulceration (days post-infection) | Time of peak of liquefaction (days post-infection) | Lesion volumes when liquefaction peaked (mm3) (mean ±SD) | Onset of healing (days post-infection) | |
|---|---|---|---|---|---|
| Control | 14 | 17 | 19 | 544.78 ± 64.89 | 31 |
| BCG | 8 | 11 | 13 | 679.66 ± 62.31 | 25 |
| Rv2626c | 13 | 16 | 18 | 521.78 ± 61.90 | 29 |
| MH | 10 | 13 | 15 | 544.05 ± 63.60 | 30 |
| EAMM | 10 | 13 | 15 | 504.35 ± 65.46 | 27 |
| EAMM-MH | 8 | 11 | 13 | 380.15 ± 53.84** | 25 |
| LT70 | 7 | 10 | 12 | 301.16 ± 40.50** | 22 |
P < 0.05 vs. Saline and BCG.