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. 2017 Feb 16;31(6):2352–2363. doi: 10.1096/fj.201601172R

Figure 4.

Figure 4.

Acute adult MS alters motivation. At the conclusion of cognitive testing, motivation was again tested with the PR task. After this testing, animals were given acute access to MS for 7 d, during which maintenance 5-CSRTT was performed, before motivation was again assessed with PR. Acute MS increased the motivation of HFD-fed offspring and offspring that had previous supplementation of methyl donors early in life. Motivation remained unchanged in control offspring. (n: SC = 14, HFD = 11, SC + MS = 13, HFD + MS = 16.) NS, not significant. #P < 0.05 compared with 0.