Table 5.
Lifetime history of suicide ideation (SI - independent) and onset of alcohol, nicotine and cannabis use and dependence (dependent) - odds ratios with their 95% Confidence Intervals from discrete-time hazard analyses (N=3,277). Models “adjusted for all covariates” report multivariate (i.e., adjusted odds – ratios; Supplemental Table S5 for covariate odds – ratios).
| Suicide ideation | Onset of Alcohol Use | Onset of Alcohol Dependence |
|---|---|---|
| Adjusted for gender, race, Hispanic and age | 0.61 (0.50, 0.75) | 1.17 (0.95, 1.44) |
| Adjusted for all covariates* | 0.71 (0.55, 0.91) not AA, M-AUD, P-AUD, B-AUD, no MDD, EDx |
1.15 (0.90, 1.45) not AA, not 22-yrs, M-AUD, P-AUD, B-AUD, no MDD, IDx, EDx |
| Onset of Nicotine Use | Onset of Nicotine Dependence | |
| Adjusted for gender, race, Hispanic and age | 0.66 (0.57, 0.77) | 1.15 (0.97, 1.36) |
| Adjusted for all covariates* | 0.74 (0.62, 0.88) S, not AA, not 22-yrs, M-AUD, P-AUD, B-AUD, not 6, 8, 10-yr FU, no MDD, EDx |
1.13 (0.93, 1.38) S, not AA, not 22-yrs, M-AUD, P-AUD, B-AUD, not 10-yr FU, no MDD, EDx |
| Onset of Cannabis Use | Onset of Cannabis Dependence | |
| Adjusted for gender, race, Hispnic and age | 0.68 (0.58, 0.79) | 1.17 (0.97, 1.41) |
| Adjusted for all covariates* | 0.77 (0.65, 0.93) S, AA, H, M-AUD, P-AUD, B-AUD not 10-yr FU, no MDD, EDx |
1.12 (0.90, 1.39) S, H, M-AUD, P-AUD, B-AUD, no MDD, IDx, EDx |
Only significant covariates are listed: AA: race is African-American; H: Hispanic; EDx: Externalizing disorders (conduct, oppositional defiant, hyperactivity-impulsivity component of attention-deficit hyperactivity-impulsivity disorder); IDx: Internalizing disorders (panic, social phobia); MDD: Major depressive disorder; M-AUD: Maternal-only history of alcohol use disorder; P-AUD: Paternal-only history of alcohol use disorder; B-AUD: Both maternal and paternal history of alcohol use disorder; 22-yrs: aged <22 at current last assessment; 2,4,6,8,10-yr FU: participation in follow-up assessments; S: Male sex.