Table 6.

Lifetime history of suicide attempt (SA - independent) and onset of alcohol, nicotine and cannabis use and dependence (dependent) - odds ratios with their 95% Confidence Intervals from discrete-time hazard analyses (N=3,277). Models adjusted for all covariates report multivariate (i.e., adjusted odds – ratios; Supplemental Table S5 for covariate odds – ratios).

Suicide Attempt	Onset of Alcohol Use	Onset of Alcohol Dependence
Adjusted for gender, race, Hispanic and age	0.94 (0.72, 1.25)	1.68 (1.21, 2.34)
Adjusted for all covariates*	1.17 (0.88, 1.55) not AA, M-AUD, P-AUD, B-AUD, no MDD, EDx	1.60 (1.12, 2.28) not AA, not 22-yrs, M-AUD, P-AUD, B-AUD, no MDD, IDx, EDx
	Onset of Nicotine Use	Onset of Nicotine Dependence
Adjusted for gender, race, Hispanic and age	1.02 (0.76, 1.37)	1.68 (1.28, 2.22)
Adjusted for all covariates*	1.19 (0.88, 1.61) S, not AA, not 22-yrs, M-AUD, P-AUD, B-AUD, not 6, 8, 10-yr FU, no MDD, EDx	1.61 (1.19, 2.17) S, not AA, not 22-yrs, M-AUD, P-AUD, B-AUD, not 10-yr FU, no MDD, EDx
	Onset of Cannabis Use	Onset of Cannabis Dependence
Adjusted for gender, race, Hispanic and age	0.94 (0.70, 1.26)	1.61 (1.21, 2.16)
Adjusted for all covariates*	1.04 (0.79, 1.38) S, AA, M-AUD, P-AUD, B-AUD, not 10-yr FU, no MDD, EDx	1.44 (1.06, 1.96) S, H, M-AUD, P-AUD, B-AUD, no MDD, IDx, EDx

^*Only significant covariates are listed: AA: race is African-American; H: Hispanic; EDx: Externalizing disorders (conduct, oppositional defiant, hyperactivity-impulsivity component of attention-deficit hyperactivity-impulsivity disorder); IDx: Internalizing disorders (panic, social phobia); MDD: Major depressive disorder; M-AUD: Maternal-only history of alcohol use disorder; P-AUD: Paternal-only history of alcohol use disorder; B-AUD: Both maternal and paternal history of alcohol use disorder; 22-yrs: aged <22 at current last assessment; 2, 4, 6, 8, 10-yr FU: participation in follow-up assessments; S: Male sex.