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Possible reasons to perform a liver biopsy in DILI
| Multiple candidates as the etiologic agent |
| Experimental agent or agent for which there is little prior record for injury |
| Gain insight into potential mechanism of injury |
| Assessment of the severity of injury to enable clinical decision |
| Known underlying liver disease |
| Alternate possible etiologies (e.g. sepsis, graft-vs-host disease) |
| Exclusion of autoimmune hepatitis |
