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TBA blood concentration in male Sprague–Dawley rats orally administered 5 mg kg−1 bw day−1 14CETBE for 1 or 14 days. Symbols represent the actual data collected 8 h following dosing on days 1, 7 and 14 (JPEC, 2008a, 2008b; see Table 2 and Supporting information), with model simulations (lines) based on model parameter values provided in Table 3. ETBE, ethyl tertiary‐butyl ether; TBA, tertiary‐butyl alcohol.
