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. 2016 Jun;14(2):33–40. doi: 10.15171/ijb.1399

Table 1. CCD of the experiments for DEE optimization utilizing DX-7 software .

Run The number of freeze/thawing cycles Eptifibatide (μmol) DSPC (mM) Cholesterol (mM) Dipalmitoyl-GRGDSPA peptide (mM) DEE (%)
1 3 1.65 6.25 3.625 0.75 0.68
2 6 2.7 7 2.75 1.5 3.31
3 3 1.65 6.25 1.875 1.25 8.62
4 8 1.65 6.25 1.875 0.75 11.16
5 8 1.65 7.75 1.875 1.25 16.29
6 3 1.65 7.75 3.625 1.25 20.25
7 6 2.7 7 2.75 0.5 3.74
8 8 3.75 7.75 1.875 0.75 24.39
9 3 3.75 7.75 1.875 1.25 25.85
10 6 0.6 7 2.75 1 27.28
11 8 1.65 7.75 3.62 0.75 27.52
12 6 2.7 5.5 2.75 1 28.14
13 6 2.7 7 1 1 29.99
14 6 2.7 7 2.75 1 27.28
15 8 3.75 6.25 1.875 1.25 32.75
16 6 2.7 7 2.75 1 35.74
17 1 27 7 2.75 1 33.63
18 8 3.75 7.75 3.625 1.25 33.65
19 6 2.7 7 4.5 1 33.68
20 6 2.7 8.5 2.75 1 34.64
21 6 2.7 7 2.75 1 36.95
22 3 3.75 6.25 3.625 1.25 36.23
23 6 4.8 7 2.75 1 37.79
24 8 1.65 6.25 3.625 1.25 26.53
25 3 1.65 7.75 1.875 0.75 28.01
26 6 2.7 7 2.75 1 30.81
27 8 3.75 6.25 3.625 0.75 29.74
28 3 3.75 7.75 3.625 0.75 35.23
29 11 2.7 7 2.75 1 35.59
30 6 2.7 7 2.75 1 28.98
31 6 2.7 7 2.75 1 33.17
32 3 3.75 6.25 1.875 0.75 5.71