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. 2017 Mar 20;34(6):1291–1306. doi: 10.1093/molbev/msx095

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© The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 5. — Distributions of accessory mutations in most and least entrenching sequences. The number of accessory mutations among the 10% “most” and “least” entrenching sequences (right and left, respectively) for the primary mutations V82A, I84V, and L90M with a fixed Hamming distance of 10 from consensus. In all three cases, the distributions are not significantly different (Mann-Whitney $U_{V 82} = 92.5, U_{V 84} = 53.0, U_{L 90} = 145.5$ , all with P > 0.05).