Table 3.
Adjusted ORs for a one-point shift in mRS at follow-up with predictor variables of SBP SD, CV and SV; stratified by lesion core volume, hypoperfused volume, mismatch volume, Target Mismatch status, proximal vessel occlusion on admission and collateral score
| BPV indices | OR* | 95% CI | p Value | BPV indices | OR* | 95% CI | p Value |
|---|---|---|---|---|---|---|---|
| Higher lesion core volume (n=55) (mean±SD=72.7±39.2 mL) | Lower lesion core volume (n=55) (mean±SD=15.1±10.3 mL) | ||||||
| SBP SD | 9.27 | 2.36 to 36.3 | 0.001 | SBP SD | 0.74 | 0.21 to 2.63 | 0.643 |
| SBP CV | 20.2 | 3.00 to 137 | 0.002 | SBP CV | 0.30 | 0.05 to 2.07 | 0.224 |
| SBP SV | 18.9 | 3.69 to 97.1 | <0.001 | SBP SV | 1.27 | 0.44 to 3.66 | 0.664 |
| Higher hypoperfused volume (n=55) (mean±SD=121.3±44.9 mL) | Lower hypoperfused volume (n=55) (mean±SD=30.5±17.6 mL) | ||||||
| SBP SD | 5.41 | 1.24 to 23.6 | 0.025 | SBP SD | 0.85 | 0.23 to 3.10 | 0.804 |
| SBP CV | 12.9 | 1.70 to 98.8 | 0.013 | SBP CV | 0.28 | 0.04 to 2.01 | 0.204 |
| SBP SV | 4.09 | 0.99 to 16.9 | 0.052 | SBP SV | 1.63 | 0.52 to 5.08 | 0.402 |
| Higher mismatch volume (n=55) (mean±SD=62.3±22.9 mL) | Lower mismatch volume (n=55) (mean±SD=11.4±10.4 mL) | ||||||
| SBP SD | 3.35 | 1.03 to 11.0 | 0.045 | SBP SD | 2.58 | 0.58 to 11.4 | 0.212 |
| SBP CV | 5.97 | 1.05 to 34.0 | 0.044 | SBP CV | 1.24 | 0.16 to 9.36 | 0.838 |
| SBP SV | 3.76 | 1.13 to 12.5 | 0.031 | SBP SV | 2.44 | 0.61 to 9.87 | 0.210 |
*Adjusted for admission NIHSS, patient sex, tPA administration, symptomatic intracranial haemorrhage and admission glucose value.
BPV, blood pressure variability; CV, coefficient of variation; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; SBP, systolic blood pressure; SV, successive variation; tPA, tissue plasminogen activator.