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. 2017 May 17;12(5):e0177785. doi: 10.1371/journal.pone.0177785

Fig 4. Total distribution volume (VT) calculated using ASIF (2-TCM) and PBIF75 (Logan plot).

Fig 4

In Temporal, Prefrontal, Hippocampus, Parietal and Occipital regions stratified as HAB and MAB groups. ASIF showed an average reduction of 29% in VT across ROIs while PBIF showed a reduction of 26%. 5/7 ROIs survived the multiple region Bonferroni adjustment using ASIF and only 2/7 passed the Bonferroni adjustment using PBIF75. Images were partial volume effect corrected prior to TAC extraction. * p< 0.05, ** p<0.01 *** p< 0.001.