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. 2016 Jan 1;37(5):1720–1734. doi: 10.1177/0271678X16646586

Table 1.

Relative haemodynamic response to SD for the various experimental phases and their duration.

A
Relative CBV responses to SD
Group Dose Phase # of measurements Hyperemia Oligemia Time of hyperemia Time of oligemia
First group, n = 5 2 mg/kg/h Before 80 21.3 ± 1.1%  − 10.2 ± 2.8% 3.02 min ± 23 s 11.03 min ± 66 s
During 46 14.0 ± 1.3%  − 13.9 ± 3.4% 2.34 min ± 25 s 8.26 min ± 77 s
After 64 13.7 ± 1.2%  − 10.6 ± 3.0% 2.21 min ± 24 s 9.16 min ± 69 s
Second group, n = 5 4 mg/kg/h Before 80 18.6 ± 1.1%  − 17.9 ± 2.8% 4.00 min ± 23 s 11.06 min ± 66 s
During
After 62 12.3 ± 1.2%  − 18.5 ± 3.0% 3.35 min ± 24 s 8.44 min ± 70 s
B
Relative arterial diameter responses to SD
Group
Dose
Phase
# of measurements
Vasodilation
Vasoconstriction
Post-SD
Time of dilation
First group, n = 5 2 mg/kg/h Before 40 39.5 ± 4.9%  − 14.3 ± 2.8% 4.1 ± 2.2% 1.90 min ± 8 s
During 23 20.4 ± 5.5%  − 13.9 ± 3.3% 5.5 ± 2.9% 1.21 min ± 10 s
After 32 15.3 ± 5.1%  − 11.4 ± 2.9% 5.7 ± 2.4% 1.36 min ± 9 s
Second group, n = 5 4 mg/kg/h Before 40 45.0 ± 4.9%  − 13.3 ± 2.8% 6.6 ± 2.2% 2.23 min ± 8 s
During
After 31 24.1 ± 5.1%  − 13.2 ± 3.0% 1.7 ± 2.5% 1.33 min ± 9 s
C
Relative CBF and CBV responses to SD
Group
Dose
Method
Phase
# of SDs
Hyperemia
Time of hyperemia
Second group, n = 4 4 mg/kg/h LDF Before 16 120.4 ± 59.6% 5.83 min ± 90 s
During
After 16 104.4 ± 50.7% 3.40 min ± 90 s
IOS Before 16 12.8 ± 4.1% 3.34 min ± 60 s
During
After 16 9.0 ± 2.3% 2.55 min ± 60 s

Values are expressed as mean and standard deviation.

CBF: cerebral blood flow; CBV: cerebral blood volume; IOS: intrinsic optical signal imaging; LDF: laser-Doppler flowmetry; SD: spreading depolarization.