Table 2. Reference standard details for EPTB diagnosis.

EPTB definition	Reference standard (Culture and /or CRS)
	MTBC Culture	Clinical symptoms	Radiologya	Histology/cytologyb	Follow-up after 3monthsc
(n = 99)	+	+	+/-	+/-	+
(n = 42)	-	+	+	+	+
(n = 8)	-	+		+	+
(n = 8)	-	+	+		+
NotTBd (n = 13)	-	+	-	-	NTe

^a: Radiological positive tests were noted when infiltrates or cavities, hilar lymph nodes, pleural effusions, or tuberculomas leptomeningeal and basal cistern enhancement were found.

^b: The histology/cytology findings of the specimen were positive with the presence of caseation necrosis and/or epithelioid granuloma.

^c: A positive response was considered if patient had received ATT and had improvement after 3 months from the date of enrollment.

^d: Culture and CRS were negative and patient had improvement without ATT

^eNT: not treated with anti-TB drugs.