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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Trends Genet. 2017 Mar 27;33(5):349–363. doi: 10.1016/j.tig.2017.03.005

Table 1. Summary of aurora kinase localization and function in mitosis and meiosis.

INCENP, inner centromere protein; ICA, inner chromatid axis; K-MT, kinetochore microtubule; MTOC, microtubule organizing center; SAC, Spindle assembly checkpoint; TPX2, targeting protein for Xklp2.

Mitosis Meiosis
Aurora Kinase Binding Partner(s) Localization Function(s) Binding Partner(s) Localization Established Function(s)
-
AURKA 		-
TPX2
Bora		 -
Spindle Poles		 -
Spindle organization		 -
TPX2
Bora		 -
Spindle Poles		 -
Spindle organization
K-MT correction
AURKB INCENP Centromeres Chromosome alignment
K-MT correction
Cohesion
SAC
Cytokinesis
Abcission
Checkpoint		 ? Microtubules Chromsome alignment
AURKC N/A N/A N/A INCENP Spindle Poles Centromeres/ICA MTOC clustering
Chromsome alignment
Chromsome condensation
K-MT correction