FIG. 1.

Map of central metabolic pathways that are involved in adenine metabolism of B. subtilis. The different enzymatic steps are represented by the corresponding gene designations. Abbreviations: pbuE, purine base efflux pump; pbuG, hypoxanthine-guanine permease; nupG, inosine-guanosine permease; pupA, adenosine phosphorylase; pupG, inosine-guanosine phosphorylase; ade, adenine deaminase; apt, adenine phosphoribosyltransferase; hpt, hypoxanthine-guanine phosphoribosyltransferase. Dashed lines indicate uncharacterized conversions.