. Author manuscript; available in PMC: 2018 May 1.

Published in final edited form as: J Am Geriatr Soc. 2017 Jan 9;65(5):966–972. doi: 10.1111/jgs.14692

Table 3.

Association of Year 4 changes in weight loss and fitness with subsequently assessed composite cognitive score by intervention assignment.

Year 4 Weight and Fitness Changes	Mean (SE) Composite Cognitive Function^*
Year 4 Weight and Fitness Changes	Diabetes Support and Education	Intensive Lifestyle Intervention

Weight loss, %
>5%	0.048 (0.039) N=425	−0.006 (0.029) N=807
0–5%	−0.000 (0.035) N=524	0.017 (0.036) N=519
Weight gain	−0.019 (0.028) N=853	0.018 (0.037) N=514
	P=0.38	P=0.83

Fitness Change, METS
>0.5 gain	0.101 (0.040) N=414	0.033 (0.034) N=579
−0.5 to 0.5 change	0.050 (0.032) N=612	0.060 (0.032) N=641
>0.5 loss	−0.000 (0.034) N=555	0.022 (0.040) N=412
	P=0.16	P=0.74

With covariate adjustment for gender, age at assessment, education, race/ethnicity, clinic, time from randomization, and the mental component score from the Short Form-36 Mental Component.