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. 2017 May 2;12:676–691. doi: 10.1016/j.dib.2017.04.043

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© 2017 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 6 — Elevated IL-6R expression delineates a subset of TIGIT⁻ mTregs with increased expression of the canonical Th17 markers CD161 and CCR6. (A) Gating strategy to delineate IL-6R^−/int (depicted in green) and IL-6R^hi (depicted in red) TIGIT⁻ mTregs. (B) Data shown depict the frequencies of the Th17 markers CD161 (N = 23) and CCR6 (N = 12) in IL-6R^−/int and IL-6R^hi mTregs, obtained by flow cytometry in freshly isolated PBMCs from healthy donors. P values were calculated using a two-tailed paired non-parametric Wilcoxon signed rank test.