Table 1.
Biodistribution (% ID/g) of radioactivity in ICR mice (n = 4) after the injection of [64Cu]PSMA-617
| Time (h) | 0.5 | 1 | 2 | 12 | 24 |
|---|---|---|---|---|---|
| Blood | 0.94 ± 0.03 | 0.9 ± 0.21 | 0.99 ± 0.29 | 1.20 ± 0.43 | 0.93 ± 0.32 |
| Heart | 1.86 ± 0.3 | 1.56 ± 0.12 | 2.23 ± 0.5 | 2.56 ± 0.66 | 2.14 ± 0.59 |
| Duodenum | 5.55 ± 0.47 | 5.81 ± 0.48 | 6.99 ± 2.56 | 3.42 ± 0.10 | 2.58 ± 0.70 |
| Kidneys | 29.42 ± 12.51 | 15.96 ± 3.09 | 7.27 ±1.17 | 4.09 ± 0.55 | 3.95 ± 0.65 |
| Liver | 12.65 ± 0.75 | 11.05 ± 2.12 | 11.4 ± 1.69 | 9.51 ± 1.06 | 9.08 ± 0.57 |
| Lung | 4.61 ± 1.05 | 5.77 ± 0.92 | 7.19 ± 1.32 | 5.13 ± 0.66 | 3.59 ± 0.86 |
| Muscle | 0.47 ± 0.16 | 0.37 ± 0.11 | 0.45 ± 0.18 | 0.50 ± 0.15 | 0.44 ± 0.15 |
| Pancreas | 1.20 ± 0.19 | 1.51 ± 0.33 | 2.40 ± 0.95 | 1.58 ± 0.47 | 1.29 ± 0.21 |
| Spleen | 1.18 ± 0.25 | 1.22 ± 0.42 | 1.45 ± 0.73 | 2.59 ± 0.80 | 1.84 ± 0.51 |
| Stomach | 2.51 ± 0.64 | 3.55 ± 0.23 | 4.99 ± 1.47 | 0.74 ± 0.10 | 1.03 ± 0.44 |