Table 2.
HOX genes down regulated in clivus chordoma cell lines compared to sacrum chordoma cell lines and the related gene ontology (GO) terms.
| GO Term | Downregulated HOX genes in clivus cell lines |
|---|---|
| Anterior-posterior pattern formation | HOXA2, HOXA4, HOXA5, HOXA7, HOXA9, HOXA10 |
| HOXB3, HOXB7 | |
| HOXC9 | |
| Skeletal development | HOXA2, HOXA4, HOXA5, HOXA7, HOXA9, HOXA10 |
| HOXB3, HOXB7 | |
| HOXC9 | |
| Regionalization | HOXA2, HOXA4, HOXA5, HOXA7, HOXA9, HOXA10 |
| HOXB3, HOXB7 | |
| HOXC9 | |
| Multicellular organismal development | HOXA2, HOXA4, HOXA5, HOXA7, HOXA9, HOXA10 |
| HOXB3, HOXB7 | |
| HOXC9 | |
| Embryonic skeletal system morphogenesis | HOXA2, HOXA4, HOXA5, HOXA7 |
| HOXB3, HOXB7 | |
| HOXC9 | |
| Developmental processes | HOXA2, HOXA4, HOXA5, HOXA7, HOXA9, HOXA10 |
| HOXB3, HOXB7 | |
| HOXC9 | |
| Anatomical structure development | HOXA2, HOXA4, HOXA5, HOXA7, HOXA9, HOXA10 |
| HOXB3, HOXB7 | |
| HOXC9 | |
| System development | HOXA2, HOXA4, HOXA5, HOXA7, HOXA9, HOXA10 |
| HOXB3, HOXB7 | |
| HOXC9 | |
| Tissue development | HOXA5 |
| HOXB3 |