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. 2017 May 17;7:2037. doi: 10.1038/s41598-017-02247-5

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Explanatory drawing of the typical pattern of changes in the virtual cardiac shapes and the end-systolic and end-diastolic left ventricular diameters of the remodeling heart. The circles indicate the endocardium of the left ventricle in each state, the end-systolic phase and end-diastolic phase. The left ventricular cavity is dilated in the end-systolic phase and/or end-diastolic phase.