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. 2017 May 17;7:1999. doi: 10.1038/s41598-017-01767-4

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Factors associated with TB and/or DM in the cohort. (A) Data represent median and interquartile ranges. The Kurskal Wallis test with Dunn’s multiple comparisons ad hoc test were employed to compare the values detected between the study subgroups. P-values for the Kruskal Wallis tests are shown in Appendix File S1. P-values were adjusted for multiple comparisons using Holm-Bonferroni’s approach as described in methods. Only comparisons with significant P-values after adjustments are displayed (*P < 0.05, **P < 0.01, ***P < 0.001). (B) Bayesian network with bootstrap (100x) was used to illustrate the statistically significant associations between the parameters and the presence of TB and/or DM in the study population. Lines represent direct associations. Associations that remained statistically significant on >30 times out of 100 bootstraps are plotted. Numbers of times each association persisted during bootstrap are shown. Bold lines highlight the strongest associations, which persisted more than 60 times in the bootstrap. Vitamin D is not presented in the picture, as it would be solitary node with no arcs attached.