Figure 3.

Mutagenesis of the OXT6 gene. (a) Illustrations of the 5′ss, 3′ss, pA1-2 and pA3 mutations. Intron-2 and 3′ UTR are shaded in yellow while exons are shaded in blue. Dots (…) represent omitted nucleotide sequences (not drawn in scale). The presumed NUE are indicated in blue, and the mutated nucleotides are indicated in red. (b) Illustrations of the complementary controls and seven OXT6 mutation constructs. Mutated regions are marked with red “Xs”.