Figure 7.

Treadmill exercise modulates nitric oxide (NO) production. Sedentary and trained mice infected or not with T. cruzi were bled at 7, 14, and 20 days post-infection (DPI) for NO measurements. NO was estimated by measuring nitrite levels via the cadmium–copper system followed by Griess reaction, as described in material and methods. (A) Levels of NO in the plasma. ^****P < 0.0001 comparing infected mice (14 and 20 DPI) with infected (7 DPI) and non-infected age matched control mice, five mice per group. (B) Levels of NO in the heart. P < 0.0001 comparing sedentary infected with sedentary uninfected and trained infected mice.