Fig. 1.

Teneligliptin effects on HUVECs viability after exposure to high-glucose conditions. HUVEC cells were incubated during 21 days under three different glucose conditions: NG (normoglycemia-5 mmol/L), HG (hyperglycemia-25 mmol/L) and NM (metabolic high-glucose memory-alternatively 5 and 25 mmol/L). Different doses of teneligliptin (0.1, 1.0 and 3.0 µmol/L) and sitagliptin (0.5 µmol/L) were used. Cell viability (%) was examined by an MTT assay. Bars represent mean ± SEM for three independent experiments