Figure 7. Spike timing‐dependent plasticity (STDP) in pairs of connected L5tt cells.

A, two reconstructed L5tt pyramidal cells located in L5B in the same column. Cells were connected reciprocally. The location of their mutual synapses is indicated by blue and green dots, respectively. B, upper panel, AP burst in the presynaptic cell evokes EPSPs in the postsynaptic cell. Unitary EPSPs before (onset) and after pairing EPSPs with postsynaptic APs for 50 min. Lower panel, time course in increase of evoked unitary EPSP amplitude after pairing as indicated (EPSPs and APs). From Markram et al. (1997 b), with permission.