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. 2017 Apr 21;102(5):489–521. doi: 10.1113/EP085776

Figure 19. Anatomical pathways that could generate broad RFs and AP burst patterns of L5tt cells.

Figure 19

Arrows between modules (square blocks) that represent the trigeminal nucleus (TN), the VPM and the PW column are anatomical connections of an individual PW projection pathway to deep layers (L6 and L5tt pyramids) of a column. Lower panel, integration across columns by layer 5tt cells via direct VPM input to the L5tt cell (red pyramid) in the PW column (foreground) and L6 cell (grey circles) inputs from a neighbouring SuW‐column pathway. For simplicity, the dense transcolumnar projections of L3 pyramidal cells to L5tt dendrites are not shown. Upper right panel, same as in lower panel but in addition the projections of spatially separate inputs to the apical oblique and the tuft dendrite zone are indicated by two arrows. A tentative AP‐burst‐generating input combination is that by VPM, L4 or L5st cell projections or by POm projections or projections from outside vS1 (upper arrow).