Figure 3.

Solvent‐prepared Aβ 25–35 fibrilizes when allowed to incubate in normal saline solution for 24 h. About 100 μm solvent‐prepared Aβ 25–35 was prepared as described in Materials and methods and allowed to aggregate in normal saline solution over a 24‐h period. Samples were taken at 0, 3, and 24 h, negative stained, and imaged using the TEM. The peptide self‐assembles over the 24‐h period. (A) No observable Aβ 25–35 species are found at the 0‐h time point. (B) No observable Aβ 25–35 species are found at the 3‐h time point. (C) Aβ 25–35 fibrils are found at the 24‐h time point. Scale bars represent 100 nm.