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. 2017 Feb 9;45(9):5501–5511. doi: 10.1093/nar/gkx109

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© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — ¹⁹F NMR shift versus concentration and temperature profiles. (A) Profiles of the relative peak areas of the ¹⁹F resonance signals versus concentration. Dimer and two-subunits stacked G-quadruplex conversions followed by ¹⁹F NMR spectroscopy. (B) Profiles of the relative peak areas of the ¹⁹F resonance signals versus temperature. Two-subunits stacked G-quadruplex/dimer G-quadruplex/single strand conversions followed by ¹⁹F NMR spectroscopy. To obtain the relative peak signal of each conformation, the total value of the relative peak signal for three conformations was estimated to be 1.0. Plotting the values of relative peak signal against temperature results in two melting curves for the two-subunits stacked Gquadruplex and dimer G-quadruplex.