Table 1. Thermodynamic parameters for RNA conformational transition.

RNA conformational transition	−ΔH (kJ/mol)	−ΔS (J/mol K)
Two-subunits G-quadruplex → Dimeric G-quadruplex	61.8	186.5
Dimeric G-quadruplex → Single strand	260.6	764.9

^aThe thermodynamic parameters were determined from van't Hoff plots (Supplementary Data). The experimental errors for enthalpy (ΔH) and entropy (ΔS) were ±5 kJ/mol and ±10 J/mol K, respectively.