Table 2.
Uni- and multivariate analyses of several parameters as predictors of recurrence-free survival
| Variables | Univariate analysis |
Multivariate analysis |
||
|---|---|---|---|---|
| Hazard ratio | p | Hazard ratio | p | |
| Age (> 70 years vs. ≤ 70 years) | 0.83 | 0.443 | – | |
| Gender (male vs. female) | 2.56 | 0.0012 | 2.79 | < 0.001 |
| Karnofsky PS (> 80% vs. ≤ 80%) | 0.90 | 0.71 | – | – |
| Body mass index (≤ 22 kg/m2 vs. > 22 kg/m2) | 1.06 | 0.82 | – | – |
| Neutrophils (> ULN vs. ≤ ULN) | 0.91 | 0.84 | – | – |
| Hemoglobin (< LLN vs. ≥ LLN) | 1.88 | 0.0061 | 0.96 | 0.87 |
| Platelets (> ULN vs. ≤ ULN) | 2.48 | 0.0033 | 1.13 | 0.73 |
| Lactate dehydrogenase (> ULN vs. ≤ ULN) | 0.75 | 0.033 | 0.76 | 0.61 |
| Corrected calcium (> 10 mg/dL vs. ≤ 10 mg/dL) | 1.07 | 0.65 | – | – |
| Albumin (< LLN vs. ≥ LLN) | 2.52 | < 0.001 | 2.00 | 0.083 |
| C-reactive protein (> ULN vs. ≤ ULN) | 1.14 | 0.22 | – | – |
| Pathological T stage (pT1 vs. pT2 or pT3) | 6.21 | < 0.001 | 2.89 | < 0.001 |
| Microvascular invasion (positive vs. negative) | 5.20 | < 0.001 | 3.26 | < 0.001 |
| Sarcomatoid component (positive vs. negative) | 4.12 | < 0.001 | 5.68 | < 0.001 |
| Geriatric Nutrition Risk Index ≤ 98 vs. > 98) | 1.82 | 0.012 | 0.82 | 0.60 |