Figure 1.

Structure and biofunctions of Cav-1. (a) The structure of Cav-1. The C-terminal, the C-terminal membrane attachment domain, and the transmembrane domain of Cav-1 are highlighted in blue, yellow, and red, respectively. The Cav-1-scaffolding domain (CSD) is responsible for Cav-1 interaction with other molecules. (b) Cav-1 biofunctions. Cav-1 is involved in the regulation of multiple physiological processes including caveola biogenesis, vesicular transport, cholesterol homeostasis, lipid transport, mitochondrial function, and signal transduction.